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?>array ( 'enabled' => true, 'seq' => 7, 'context' => 2, ); ?>array ( 'enabled' => true, 'seq' => 1, 'context' => 2, ); ?>array ( 'context' => 2, 'enabled' => true, 'seq' => 6, ); ?>array ( 'context' => 2, 'enabled' => true, 'seq' => 3, ); ?>array ( 'context' => 2, 'enabled' => true, 'seq' => 4, ); ?>array ( 'context' => 2, 'enabled' => true, 'seq' => 2, ); ?>array ( 'enabled' => true, 'seq' => 9, 'context' => 2, ); ?>array ( 'enabled' => true, 'seq' => 0, 'context' => 2, ); ?>array ( 'context' => 2, 'enabled' => true, 'seq' => 5, ); ?>array ( 'enabled' => true, 'seq' => 8, 'context' => 2, ); ?> Valoración de la fiabilidad de los test neurológicos en modelos de ictus isquémico en roedores | Turiel García | REDUCA

Valoración de la fiabilidad de los test neurológicos en modelos de ictus isquémico en roedores

Irene Turiel García, Eva Álvarez Torres, Fernando Arnáiz Guerrero

Resumen


el ictus es la enfermedad neurológica de mayor prevalencia y presenta una gran morbilidad y alto riesgo de mortalidad. Para estudiarla se han desarrollado distintos modelos animales; siendo los roedores un ejemplo excelente. Nuestro objetivo es valorar la fiabilidad de tres test neurológicos: beam walking, cylinder test y the modified Neurological Severity Scale (mNSS) en ratones Swiss tras una isquemia. Nuestros resultados sugieren que a pesar de que la población analizada es pequeña, cylinder test y mNSS muestran una diferencia estadísticamente significativa en las poblaciones SHAM y pMCAO a las 24 y 48h postisquemia mientras que el beam walking sólo mostró diferencias estadísticamente significativo a las 48 postisquemia.

Palabras clave


Ictus; Isquemia; ACM; Test neurológico;

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