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	<title>La microcirugía hepática experimental: un método para estudiar la patología utilizando mecanismos embrionarios | Fernández Morales | REDUCA</title>
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			<meta name="keywords" content="Hígado; Microcirugía; Embriología; Reacción ductular; Colestasis; Hepatectomía; Hipertensión portal;" />
	
	
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	<meta name="DC.Description" xml:lang="es" content=" Las técnicas microquirúrgicas en la actualidad son utilizadas para crear modelos experimentales en la rata que permitan estudiar la patología hepática que sufre el ser humano. Destacan los modelos que se fundamentan en la siguientes técnicas microquirúrgicas: colestasis extrahepática, anastomosis porto-cava termino-terminal, hipertensión portal por triple ligadura parcial de la vena porta, ligadura parcial de la vena cava inferior suprahepática y hepatectomías parciales. Los modelos experimentales microquirúrgicos obtenidos se propone que sufren una patología hepática que se fundamenta en la recapitulación de mecanismos embrionarios. En particular, destaca la existencia de una reacción ductular similar a la existente en las primeras fases del desarrollo embrionario del hígado. Ya que la respuesta ductular en los modelos experimentales de patología hepática es inducida por mecanismos inflamatorios, se sugiere en el presente trabajo que dichos mecanismos son fundamentales en el hígado tanto para su desarrollo embrionario como para la inducción de múltiples patologías. "/>
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								<meta name="DC.Subject" xml:lang="es" content="Microcirugía"/>
								<meta name="DC.Subject" xml:lang="es" content="Embriología"/>
								<meta name="DC.Subject" xml:lang="es" content="Reacción ductular"/>
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				<meta name="DC.Title" content="La microcirugía hepática experimental: un método para estudiar la patología utilizando mecanismos embrionarios"/>
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        <meta name="citation_author" content="David Fernández Morales"/>
        <meta name="citation_author" content="Isabel Mª Peral Martínez"/>
        <meta name="citation_author" content="María Ramírez"/>
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	<div id="articleTitle"><h3>La microcirugía hepática experimental: un método para estudiar la patología utilizando mecanismos embrionarios</h3></div>
	<div id="authorString"><em>David Fernández Morales, Isabel Mª Peral Martínez, María Ramírez</em></div>
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		<h4>Resumen</h4>
		<br />
		<div>Las técnicas microquirúrgicas en la actualidad son utilizadas para crear modelos experimentales en la rata que permitan estudiar la patología hepática que sufre el ser humano. Destacan los modelos que se fundamentan en la siguientes técnicas microquirúrgicas: colestasis extrahepática, anastomosis porto-cava termino-terminal, hipertensión portal por triple ligadura parcial de la vena porta, ligadura parcial de la vena cava inferior suprahepática y hepatectomías parciales. Los modelos experimentales microquirúrgicos obtenidos se propone que sufren una patología hepática que se fundamenta en la recapitulación de mecanismos embrionarios. En particular, destaca la existencia de una reacción ductular similar a la existente en las primeras fases del desarrollo embrionario del hígado. Ya que la respuesta ductular en los modelos experimentales de patología hepática es inducida por mecanismos inflamatorios, se sugiere en el presente trabajo que dichos mecanismos son fundamentales en el hígado tanto para su desarrollo embrionario como para la inducción de múltiples patologías.</div>
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		<h4>Palabras clave</h4>
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		<div>Hígado; Microcirugía; Embriología; Reacción ductular; Colestasis; Hepatectomía; Hipertensión portal;</div>
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		<h4>Texto completo:</h4>
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