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	<meta name="DC.Description" xml:lang="es" content=" El desarrollo de la microcirugía ha dependido siempre de la experimentación animal. La microcirugía puede constituir una técnica válida para  mejorar modelos experimentales de enfermedades hepáticas debido a que reduce las complicaciones quirúrgicas. La microdisección y las microsuturas son consideradas técnicas microquirúrgicas principales para el desarrollo de modelos experimentales en la rata  y, por lo tanto para  la investigación de la patología hepática. La ligadura parcial de la vena porta, la colestasis extrahepática y las hepatectomías son modelos experimentales basados en microdisección. Por otra parte, entre las técnicas de microsuturas destacan  la anastomosis portacava, el trasplante  ortotópico de hígado y el trasplante heterotópico parcial hepático. Si los modelos experimentales creados para la investigación hepática son desarrollados con éxito, los resultados obtenidos de sus estudios serían particularmente útiles en pacientes con enfermedades hepáticas. "/>
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	<div id="articleTitle"><h3>50 años 1961 - 2011 aplicando la microcirugía experimental  para estudiar la patología hepática</h3></div>
	<div id="authorString"><em>María Ramírez Sánchez, Isabel Mª Peral Martínez, David Fernández Morales</em></div>
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		<h4>Resumen</h4>
		<br />
		<div>El desarrollo de la microcirugía ha dependido siempre de la experimentación animal. La microcirugía puede constituir una técnica válida para  mejorar modelos experimentales de enfermedades hepáticas debido a que reduce las complicaciones quirúrgicas. La microdisección y las microsuturas son consideradas técnicas microquirúrgicas principales para el desarrollo de modelos experimentales en la rata  y, por lo tanto para  la investigación de la patología hepática. La ligadura parcial de la vena porta, la colestasis extrahepática y las hepatectomías son modelos experimentales basados en microdisección. Por otra parte, entre las técnicas de microsuturas destacan  la anastomosis portacava, el trasplante  ortotópico de hígado y el trasplante heterotópico parcial hepático. Si los modelos experimentales creados para la investigación hepática son desarrollados con éxito, los resultados obtenidos de sus estudios serían particularmente útiles en pacientes con enfermedades hepáticas.</div>
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		<h4>Palabras clave</h4>
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		<div>Microcirugía; Anastomosis porto-cava; Colestasis; Hepatectomías; Trasplante de hígado;</div>
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